Modelling Resistance to Emerging Epigenetic Therapies
نویسندگان
چکیده
منابع مشابه
Emerging epigenetic targets and therapies in cancer medicine.
UNLABELLED Abnormalities in the epigenetic regulation of chromatin structure and function can lead to aberrant gene expression and cancer development. Consequently, epigenetic therapies aim to restore normal chromatin modification patterns through the inhibition of various components of the epigenetic machinery. Histone deacetylase and DNA methyltransferase inhibitors represent the first putati...
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ژورنال
عنوان ژورنال: Blood
سال: 2014
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v124.21.3546.3546